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In vitro ADME Screening Services

Drug developers increasingly require faster and more predictive compound screens to reduce time-to-market and develop safer drugs. Using high-throughput mass spectrometry for in vitro ADME applications, the RapidFire system enables researchers to gain a more complete understanding of the biochemical properties of potential lead compounds, including potential liabilities due to drug-drug interactions. Uncovering these potential complications during the earliest stages of discovery permits researchers to select only the most promising candidates for further development, thus saving time and money by focusing their resources on the compounds that are most likely to succeed.

CYP Inhibition Screening
The RapidFire CYP Inhibition Screening Service provides high quality mass spectrometry based CYP inhibition assay data using FDA recommended drug probes and liver microsomes providing data that correlates with conventional LC-MS techniques.

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Metabolic Stability