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RapidFire High Throughput Mass Spectrometry System
Label-free detection, online sample preparation and automated 24/7 processing for lead discovery and in vitro ADME applications.
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BIOCIUS Label-free Detection Products

The RapidFire® High-throughput Mass Spectrometry (RF-MS) System is a native detection technology for the screening of chemical libraries against biochemical assays and in vitro ADME assay analyses. The RF-MS system facilitates the label-free detection of multiple analytes in a wide range of applications in seconds per sample, greatly streamlining assay development and providing biologically relevant data.

The system features integrated, online sample preparation—simply quench your assay plates and load them into the RapidFire for analysis. The system is compatible with SBS standard 96 and 384 well plates, including deep-well and low-volume plates. Accommodating up to 18 plates at once, RF-MS enables walk-away processing of sample for hours.

RapidFire technology helps to maximize your mass spectrometer resource, as conversion between RF-MS and HPLC-MS is fast and easy. Data analysis and report generation software permits export into spreadsheets and databases in formats compatible with any LIMS. Integration of the RapidFire is easy with any leading manufacturer’s mass spectrometer. Incorporation of a RapidFire-MS into existing laboratory workflows is straightforward for a variety of lead discovery and in vitro ADME applications,

Use RapidFire for these drug discovery applications
High-throughput
screening assays
  in vitro ADME assays
  • Methylases
  • Acetylases
  • Lipids
  • HDACs
  • and more
 
  • CYP Inhibition
  • Metabolic Stability
  • Permeability
  • CYP Induction
  • Plasma Protein Binding

 

 

 

 

 

BIOCIUS. Faster Answers.

RapidFire® technology is described in patent numbers 6,932,939, 6,812,030 7,100,460, 7,588,725,